Publications

SELECTED PUBLICATIONS (from over 40 published articles)

1. Nagendra S Ningaraj, Divya Khaitan,  (2015) Targeting Ion Channels for Drug Delivery to Brain Tumors, Frontiers in Anti-Cancer Drug Discovery- , Vol. 5, Pages 231-246, Eds. Atta-Ur- Rahman & Iqbal Choudhary, Bentham Science Publishers Ltd. University of Cambridge, UK.
2. Ningaraj, N. S., Khaitan, D, (2013)Targeting Potassium Channels for Increasing Delivery of Imaging Agents and Therapeutics to Brain Tumors,  Front. Pharmacol. 4:62. doi:10.3389/ fphar.
3. Khaitan, D., Sankpal, U., and Ningaraj, S. (2009) Role of KCNMA1 gene in breast cancer invasion and metastasis to brain.  BMC Cancer, 9:258, 1-11.
4. Ningaraj NS, Umesh T. Sankpal, Divya Khaitan, Edward A. Meister, Trib Vats (2009),  KCa channel Modulation Increases Anticancer Drug Delivery to Brain Tumors, Cancer Biology and Therapy, 8 (20), 1-10.
5. Ningaraj NS. (2009) Activation of KATP Channels Increases anticancer drug delivery to Brain Tumor and survival, European Journal of Pharmacology 602: 188-193.
6. Ningaraj NS, Salimath BP, Sankpal UT, Perera R, Vats T, Targeted Brain Tumor Treatment Treatment-Current Perspectives. Drug Target Insights 2008:2  1-11.
7.  Ningaraj NS (2006), Progress and Challenges of Drug Delivery to Brain Tumors, Expert Opinion on Drug Delivery. 3:499-509.
8. Ningaraj, NS, Black KL. (2004) Biochemical Modulation of Abnormal Brain Capillaries for Enhanced and Selective Drug Delivery. Cancer Control 11: 165-173.
9. Ningaraj NS et al.  (2003) ATP-Sensitive Potassium Channel-Mediated Blood Brain Tumor Barrier Permeability Increase in a Rat Brain Tumor Model. Cancer Res. 63:8899-8911.
10. Ningaraj, NS et al. (2003) Calcium-dependent potassium channels as a target protein in the modulation of blood-brain tumor barrier, Drug News and Perspectives 16 (5):291-298.
11. Ningaraj NS et al. (2002) Regulation of Blood-Brain Tumor Barrier Permeability by Calcium-Activated Potassium Channels. J Pharmacol Expt Ther. 301:838-851.
12. Ningaraj NS, Schloss J.V., Faiman M.D, Wu J.Y.  (2001) S-Methyl N, N-diethylthiolcarbamate      Sulfoxide   Elicits Neuroprotective effect against NMDA Receptor-mediated Neurotoxicity. J. Biomed. Sci. 8:104-113.
13. Jang-Yen Wu, Hong Jin, Schloss J.V., Faiman M.D, Ningaraj NS, Chen W. (2001) Neurotoxic effect of  acamprosate, N-acetyl-homotaurine, in cultured neurons. J. Biomed. Sci. 8:96-103.
14. Liu Y, Hashizhume K, Somato K, Chen Z, Ningaraj NS and Black K. (2001) Correlation  between bradykinin-induced blood tumor barrier permeability and B2 receptor Expression in Experimental Brain Tumors.  Neurological Res. 23:379-387.
15. Liu Y, Hashizhume K, Somato K, Sugita M, Ningaraj NS, Asotra K and Black K. (2001) Repeated, Short-term Ischemia Augments Bradykinin-Mediated Opening of Blood Tumor Barrier in Rats with RG2 Glioma. Neurological Res. 23:631-640.
16. Ningaraj NS, Schloss J.V., Faiman M.D, and Wu J.Y.  (2001) S-Methyl N, N-diethylthiolcarbamate   Sulfoxide Elicits Neuroprotective effect against NMDA Receptor-mediated Neurotoxicity. J. Biomed. Sci. 8:104-113.
17. Jang-Yen Wu, Hong Jin, Schloss J.V., Faiman M.D, Ningaraj NS, Chen W. (2001) Neurotoxic effect of acamprosate, N-acetyl-homotaurine, in cultured neurons  J. Biomed. Sci. 8:96-103.
18. S.N. Nagendra (Ningaraj NS) and Mamatha R.K. (1998) Disulfiram Augments Oxidative Stress on Rat Brain following Bilateral Carotid Artery Occlusion. J. Biomed. Sci. 5: 226-230.
19. Ningaraj NS, Schloss J.V. Williams, T.D. Faiman M.D. (1998) Glutathione  Carbamoylation with S-Methyl N, N-diethylthiolcarbamate Sulfoxide and Sulfone: Mitochondrial Low Km Aldehyde Dehydrogenase Inhibition and Implications for its Alcohol Deterrent Action. Biochem. Pharmacol. 55 (6) 749-756.
20.  Nagendra S.N (Ningaraj NS), Faiman M.D, Davis K., Wu J.Y., Newby X and Schloss J.V. (1997), Carbamoylation of Brain Glutamate Receptors by a Disulfiram Metabolite. J. Biol.Chem. 272 (39): 24247-24251.

Book Chapters
Book Chapters
1. Liu, G., Nagendra S.N, Wu, J.-Y., Faiman, M.D. and Schloss, J.V. (1999). The fate of S- carbamoylating agents in vivo and in vitro, In: Enzymatic Mechanisms, Frey, P.A. and Northrop, D.B., Eds. IOS Press, Amsterdam, 107-115.
2. Asotra, K., Ningaraj NS, and Black, K.L. (2002).  Measurement of Blood-Brain and Blood-Tumor Barrier Permeabilities with [14C]-Labeled Tracers.  In: The Blood Brain Barrier: Biology and Research Protocols, Methods in Molecular Biology series, Sukriti Nag, MD, PhD, FRCP (Ed.), Humana Press, Totowa, NJ.
3. Nagendra S Ningaraj, Divya Khaitan,  (2015) Targeting Ion Channels for Drug Delivery to Brain Tumors, Frontiers in Anti-Cancer Drug Discovery- , Vol. 5, Pages 231-246, Eds. Atta-Ur- Rahman & Iqbal Choudhary, Bentham Science Publishers Ltd. University of Cambridge, UK.
4. Divya Khaitan, Polluru L Reddy, Divya S. Narayana, Nagendra SN. (2017- In press), Volume XXVI: Imaging, Molecular Diagnostics and Cancer treatment: Recent Advances in Understanding of Blood-brain Tumor Barrier (BTB) Permeability Mechanisms that Enable Better Detection and Treatment of Brain Tumors, Elsevier Publishing co., Academic Press, Amsterdam, Netherlands.
From 12 submitted/issued Patents (US/ EU and Japan)
1. Method for using potassium channel agonists for delivering a medicant to An abnormal brain region and/or a malignant tumor-Patent No. US7, 018,979B1 (Application No. US09/491,500) 2006
2. (WO/2005/025511) Potassium channel mediated delivery of agents through the blood-brain barrier 2003
3. Induction of apoptosis of malignant cells by activation of calcium-activated potassium channels- USPTO Application #: 20060280730 (2006).
PUBLICATIONS
1. Divya Khaitan and Nagendra S. Ningaraj.Targeting potassium channels for increasing delivery of imaging agents and therapeutics to brain tumors. Front. Pharmacol., 29 May 2013 | doi: 10.3389/fphar.2013.00062
2. Joseph Mazar, Divya Khaitan, Dan DeBlasio, Cuncong Zhong,Subramaniam S. Govindarajan, Sharmila Kopanathi, Shaojie Zhang,Animesh Ray, and Ranjan J. Perera. Epigenetic Regulation of MicroRNA Genes and the Role of miR-34b in Cell Invasion and Motility in Human Melanoma. PLoS One. 2011; 6(9): e24922
3. http://www.humanhealthandscience.com/rna-spurs-melanoma-development-potential-new-diagnostic-marker-for-skin-cancer/general/cancer
4. Verma Amit; Bhatt Anant Narayan; Farooque Abdullah; Khanna Suchit;Khaitan Divya; Arya Mohan B; Arya Anu; Dhawan Ashish; Raj Hanumantharao G; Saluja Daman; Prasad Ashok K; Parmar Virinder S; Dwarakanath Bilikere S 7, 8-diacetoxy-4-methylcoumarin induced cell death in human tumor cells is influenced by calreticulin.Biochimie 2011;93(3):497-505
5. Divya Khaitan, Marcel E. Dinger, Joseph Mazar, Joanna Crawford, Martin A. Smith, John S. Mattick, and Ranjan J. Perera. The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Research, 2010; 71(11); 1–11.
6. Joseph Mazar, Katherine DeYoung, Divya Khaitan, Edward Meister, Alvin Almodovar, James Goydos, Animesh Ray, and Ranjan J. Perera. The regulation of miRNA-211 expression and its role in melanoma cell invasiveness. PLoS One. 2010; 5(11): e13779.
7. Divya Khaitan and B.S. Dwarakanath. Radiosensitization and chemosensitization of multicellular tumor spheroids by 2-deoxy-D-glucose is stimulated by a combination of TNFa and glucodeprivation induced oxidative stress. In Oxidative Stress. In “Oxidative Stress in Clinical Practice:Cancer”Springer – Humana Press (2009).
8. Ananth N Bhatt, Divya Khaitan and B. S. Dwarakanath. Role of metabolic oxidative stress in the radiation response of cells: Implications for therapy and protection. In Proc of SFRR Conference. (2009).
9. Divya Khaitan, Sudhir Chandna and B. S. Dwarakanath. Short term exposure of multicellular spheroids from a human glioma cell line to 2-DG leads to higher toxicity than long term exposure. J Cancer Res Ther2009,5(9): 67-73, 2009.
10. 10.  Divya Khaitan, Sankpal, U., and Ningaraj, S. Role of KCNMA1 gene in breast cancer invasion and metastasis to brain.  BMC Cancer, Vol. 9, No. 1. (29 July 2009), 258.
11. Ningaraj NS, Umesh T. Sankpal, Divya Khaitan, Edward A. Meister, Trib Vats  Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model . Cancer Biology and Therapy, 8, (20): 36 – 45, 2009.
12. Ningaraj NS, Umesh T. Sankpal, Divya Khaitan, Edward A. Meister, Trib Vats Activation of KATP Channels Increases anticancer drug delivery to Brain Tumor and survival, European Journal of Pharmacology 602:188-193, 2009.
13. Shubhankar Suman, Divya Khaitan, Rakesh Kumar Seth, and Sudhir  Chandna Stress response of a p53 homologue in the Radioresistant Sf9 insect cells. International Journal of Radiation Biology 85: 238- 249, 2009.
14. Divya Khaitan and B.S. Dwarakanath. Endogeneous and induced oxidative stress in multicellular tumor spheroids: Implications for improving therapy.Ind J Biochem Biophys, 46: 16-24, 2009.
15. Divya Khaitan, Sudhir Chandna, M.B. Arya and B.S. Dwarakanath. Establishment and characterization of multicellular spheroids from a human glioma cell line: Implication for tumor therapy. J. Translat. Med. 4, 12. 2006.
16. Divya Khaitan, S. Chandna, M.B. Arya and B.S. Dwarakanath. Differential mechanisms of radiosensitization by 2-Deoxy-D-Glucose in the monolayers and multicellular spheroids of a human glioma cell line. Cancer Biol. Ther. 5(9): 1142-1151, 2006.
17. Divya Khaitan and B.S. Dwarakanath. Multicellular spheroids as an in vitromodel in experimental oncology: applications in translational medicine.Expert opinion in Drug Discov. 2006, 1(7), 663-675.
18. Dwarakanath BS, Adhikari JS, Divya Khaitan, Chandna S, Mathur R and Ravindranath T. Growth inhibition and induction of apoptosis by 2-deoxy-D-glucose in human squamous carcinoma cell lines. Biomedicine. 24(3): 36-47, 2005.
19. Adhikari JS, Divya Khaitan, Arya MB and Dwarakanath BS. Heterogeneity in the radiosensitizing effects of the DNA ligand Hoechst-33342 in human tumor cell lines. J. Cancer Res. Ther. 1(3): 151-161, 2005.
20. Chandna S, Dwarakanath BS, Seth RK, Divya Khaitan, Adhikari JS and Jain V. Radiation Response of Sf9, a highly radioresistant lepidopteran insect cell line. Int. J. Radiat. Biol. 80: 301-315, 2004.
21. Dwarakanath BS, Divya Khaitan and Ravindranath T. Two-Deoxy-D-glucose enhance the cytotoxic effects of topoisomerase inhibitors in human tumor cell lines. Cancer Biol. Ther. 3: 34-43, 2004.
22. Dwarakanath BS, Divya Khaitan and Mathur R. Inhibitors of topoisomerases as anticancer drugs: Problems and Prospects. Ind. J. Expt. Biol. 42: 649-659, 2004.
23. Chandna S, Dwarakanath BS, Divya Khaitan, Mathew TL and Jain V. Low dose ionizing radiation hypersensitivity in human tumour cell lines: Effects of cell-cell contact and nutritional deprivations. Rad. Res. 157: 516-525, 2002.
24. Tawar U, Jain AK, Dwarakanath BS, Chandra R, Singh Y, Chaudhury NK,Divya Khaitan and Tandon V. Influence of phenyl ring disubstitution on bisbenzimidazole and terbenzimidazole cytotoxicity: synthesis and biological evaluation as radioportecots. J. Med. Chem. 46: 3785-3792, 2002.
Book Chapter
1. Nagendra S Ningaraj, Divya Khaitan, Targeting Ion Channels for Drug Delivery to Brain Tumors, Frontiers in Anti-Cancer Drug Discovery- Benthem Science (2014)- In press
POLURU  L. REDDY, Ph.D. DABCC
PUBLICATIONS:
1.        Reddy, P.L., Narayanan, H.S., Channabasavanna, S.M., Mohan, K.S., Sarmukaddam, S., Joseph, D.M. & Rao, B.S.S. (1987). “A study of mode of inheritance in 100 subjects with manic depressive psychosis”. NIMHANS Journal 6: 7-11.
2.        Reddy, P.L., Mohan, K.S., Subhash, M.N., Channabasavanna, S.M. & Rao,  B.S.S. (1987). “Biochemical-genetic markers and psychiatric disorders”. Bulletin of Human Genetics 12: 16-19.
3.         Reddy, P.L., Sarmukaddam, S.B., Mohan, K.S., Narayanan, H.S., Channabasavanna, S.M. & Rao, B.S.S. (1987). “Genetic studies in psychiatric disorders with special reference to significance of orders of birth”. In A. Chowdhary & S.B. Roy (Eds) Contemporary Studies in Mother Child Health Status. 1: 45-47.
4.         Channabasavanna, S.M., Narayanan, H.S., Mohan, K.S., Joseph, D.M., Sarmukaddam, S.B., Reddy, P.L., & Rao, B.S.S. (1987). “Genetic investigations in patients with affective disorders”. In S.M. Channabasavanna & Shah (Eds) Affective Disorders: Recent Research and Related Developments. Bangalore, NIMHANS. pp. 97-102.
5.         Reddy, P.L., Puttaram, S., Rao, B.S.S., Khanna, S. & Channabasavanna, S.M. (1988). “Blood groups and affective disorders.  Indian J. Psychiat. 30: 403-404.
6.        Rao, B.S.S., Mohan, K.S., Sapru, M.K., Reddy, P.L., & Gopinath, P.S. (1989). “Platelet monoamine oxidase and plasma dopamine beta hydroxylase in patients with schizophrenia”. Indian Journal of Clinical Biochemistry 4: 47-49.
7.        Reddy, P.L., Khanna, S., Subhash, M.N., Channabasavanna, S.M. & Rao, B.S.S. (1989). “Erythrocyte membrane Na-K ATPase activity in affective disorder”. Biological Psychiatry. 26: 533-537.
8.        Reddy, P.L., & Rao, B.S.S. (1990). “Inheritance models in major psychiatric disorders”. Bulletin of Human Genetics. 15: 1-5.
9.        Khanna, S., Gokul, B.N., Reddy, P.L., & Channabasavana, S.M. (1990). “Humoral immune function in obsessive compulsive disorder”. Indian Journal of Psychological Medicine. 13: 31-37.
10.        Reddy, P.L., (1990). “Molecular loop lesion correction: A model for the mechanism of action of lithium in affective disorders”. In B.S.S. Rao and S.C. Bondy (eds) Proceedings of Indo-US Symposium on Molecular Mechanisms Underlying Neuronal Response to Damage, pp 173-180.
11.        Khanna, S., Reddy, P.L., (1990). “Neuronal toxicity due to lithium: clinical manifestations”.  In B.S.S. Rao & S.C. Bondy (Eds) Proceedings of Indo-US Symposium on Molecular Mechanisms Underlying Neuronal Response to Damage pp 181-183.
12.        Reddy, P.L., Khanna, S., Subhash, M.N., Channabasavanna, S.M., and Rao B.S.S. (1992). ” CSF amine metabolites in depression”. Biological Psychiatry 31: 112-118.
13.        Reddy, P.L., Khanna, S., Subhash, M.N., Channabasavanna, S.M., and Rao B.S.S. (1992). “Erythrocyte membrane sodium potassium adenosine triphosphatase activity in affective disorders”. Journal of Neural Transmission. 89: 209-218.
14.        Veeranna, Reddy, P.L., and Bhargava, H.N. (1992). “Abstinence from U-50,488H, a kappa opiate receptor agonist, decreases the binding of [3H] DPAT to 5-HT1A receptors in the hypothalamus of the rat”.  Neuropharmacology 31: 1243-1249.
15.        Khanna, S., Reddy, P.L., Subhash, M.N., Channabasavanna, S.M., & Rao, B.S.S. (1992). “Multiple neuroendocrine responses to clonidine in obsessive compulsive disorder”. Indian Journal of Psychiatry . 34: 264-270.
16.        Reddy, P.L., Veeranna, Thorat, S.N. and Bhargava, H.N. (1993). “Evidence for the behavioral supersensitivity of dopamine D2 receptors without receptor up-regulation in morphine abstinent rats”. Brain Res. 293-300.
17.        Thorat, S.N., Veeranna., Reddy, P.L.. and Bhargava, H.N. (1993). “Biochemical and behavioral studies on the interaction between ì- and k-opiate agonists in mice”. Brain Res. 615, 191-198.
18.        Veeranna., Reddy, P.L., and Bhargava, H.N. (1993). “Effect of chronic administration of U-50,488H, a kappa receptor agonist, on central dopamine D2 receptors of the rat”. Eur. J. Pharmacol. 235: 23-30.
19.        Thorat, S.N., Reddy, P.L.. and Bhargava, H.N. (1993). “Evidence for the role of nitric oxide in k-opiate tolerance in mice”. Brain Res. 621: 171-174.
20.        Reddy, P.L.., Veeranna, Matwyshyn, G.A., Thorat, S.N. and Bhargava, H.N. (1994). “Effect of morphine tolerance and abstinence on the binding of 3H-naltrexone to discrete brain regions and spinal cord of rat”. General Pharmacology  25: 355-361.
21.        Bhargava, H.N., Matwyshyn, G.A., Reddy, P.L.. and Veeranna (1994) “Brain and spinal cord kappa opiate receptors and pharmacological responses to U-50,488H in rats of differing ages”. Pharmacology, Biochemistry and Behavior  48: 87-91.
22.        Bhargava, H.N., Matwyshyn, G.A., Reddy, P.L.. and Veeranna (1994) “Effect of naltrexone on the binding of 3H-D-Ala2, MePhe4, Gly-ol5 – enkephalin to brain regions and spinal cord and pharmacological responses to morphine in the rat”. Gen. Pharmacol  24: 1351-1357.
23.        Gudehithlu, K.P.,  Reddy, P.L. and Bhargava, H.N (1994) “Effect of morphine tolerance and abstinence on the binding of 3H-MK 801 to brain regions and spinal cord of the rat”.  Brain Res. 639: 269-274.
24.        Javaid, I.J., Notorangelo, M.P., Pandey, S.C., Reddy, P.L., Pandey, G.N and Davis, J.M (1994) “Peripheral benzodiazepine receptors are decreased during cocaine withdrawal in humans”. Biological Psychiatry, 36: 44-50.
25.        Bowie, L.J., Reddy, P.L., Nagabhushan, M and Pierre, S. (1994) “The detection of alpha thalassemias by multiplex polymerase chain reaction”. Clinical Chemistry, 40: 2260-2266.
26.        Bhargava, H.N., Reddy, P.L. and Gudehithlu, K.P (1995) “Effect of morphine tolerance and abstinence on N-methyl D-aspartate receptors of brain regions and spinal cord of the rat”.  General Pharmacology, 26: 131-136.
27.        Reddy, P.L and Bhargava, H.N. (1996) “Effect of low pH treatment on opioid          peptides binding to their receptors and functional coupling of ‘G’ proteins to   adenylyl cyclase in the rat spinal cord”. Peptides. 17:  625-628.
28.        Bowie, L.J and Reddy, P.L. (1997) “Alpha thalassemia and its impact on other clinical conditions”. Clinics in Laboratory Medicine , 17: 97-108.
29.        Reddy, P.L. and Bowie, L.J. (1997) “Sequence based diagnosis of hemoglobinopathies in the clinical laboratory”. Clinics in Laboratory Medicine, 17: 85-96.
30.        Reddy, P.L., Bowie, L.J and Callistein, S. (1997) “The binding of nitric oxide to thiols and hemes of hemoglobin H: Implications for alpha thalassemia and             hypertension”. Clinical Chemistry, 43: 1442-1447.
31.        Bowie, L.J and Reddy, P.L. and Nowak, E.M (1998) Alpha thalassemia     subtyping and the detection of silent mutations by high resolution fragment analysis and DNA sequencing.  Molecular Diagnosis, 3: 43-53.
32.       Reddy, P.L., Bowie, L.J.,Jiang, H. (2000) Blood pressure changes after intravenous administration of cell free hemoglobin H and hemoglobin A in rats. Nitric oxide4:139-146.
33.       Raza, A., Zorat, F., Nascimben, F., Mundle, S., Shetty, V., Reddy ,P., Allampallam, K., Alvi, S., Shaher, A., Ansaari, M., Venugopal, P (2000) A view of mylodysplastic syndromes as an infectious disease: viruses, stroma and new strategies for therapy.  In Karel A. Dicke & Armand Keating (eds); “Autologous Blood and Marrow Transplantation”: Proceedings of the Tenth International Symposium, Cardens Jennings Publishing, Charlottesville, Virginia, USA; pp 302-311.
34.       Alvi, S., Shaher, A., Shetty, V., Henderson, B., Dangerfield, B., Zorat, F., Joshi, L., Anthwal, S., Lisak, L., Little, L., Gezer, S., Mundle, S., Reddy, P.L., Allampallam, K., Huang, X., Galili, N., Borok, R.Z., Raza, A: (2001) Successful establishment of long term bone marrow cultures in 103 patients with myelodysplastic syndromes. Leukemia Research 25, 941-954.
35.       Reddy, P.L., Shetty, V.T., Dutt, D., York, A., Dar, S., Mundle, S.D., Allampallam, K., Alvi, S., Galili, N., Saberwal, G.S., Anthwal, S., Shaikh, M., Suleman, S., Kamal, S.Y., Raza, A (2002): Increased incidence of mitochondrial cytochrome c-oxidase gene mutations in patients with myelodysplastic syndromes.  British Journal of hematology 116, 564-575.
36.       Shetty, V., Hussaini, S., Broady-Robinson, L., Alvi, S., Joshi. L., Shaher. A., Dangerfield, B., Nascimben, F., Mundle, S., Allampallam, K., Reddy, P., Galili, N., Raza, A. (2002) Ultrastructural studies of bone marrow biopsies in myelodysplastic syndromes show excessive apoptosis, increased phagocytosis, nuclear inclusion bodies and cylindrical confronting cisternae. British Journal of hematology 116, 817-825.
37.       Allampallam, K., Shetty, V., Mundle, S., Dutt, D., Reddy, P.L., Alvi, S., Galili, N., Saberwal, G.S., Anthwal, S., Shaikh, M., Raza, A. (2002) Cytokines, apoptosis and macrophages – their biologic and clinical significance in 145 patients with myelodysplastic syndrome. International Journal of hematology, 75:289-297.
38.       Raza A, Buonamici S, Lisak L, Tahir S, Donglan L, Imran M, Chaudary NI, Pervaiz H, Gallegos JA, Alvi MI, Mumtaz M, Gezer S, Venugopal P, Reddy P, Galili N, Candoni A, Singer J, Nucifora G,(2004)  Arsenic trioxide and thalidomide combination produces multi-lineage hematologic responses in myelodysplastic syndomes patients, particularly in those with high pre-therapy EV11 expression.  Leuk. Res.28(8):791-803
39.       Raza A, Candoni A, khan U, Lisak L, Tahir S, Silvestri F, Billmeier J, Alvi MI, Mumtaz M, Gezer S, Venugopal P,Reddy P, Galili N. (2004). Remicade as TNF suppressor in patients with myelodysplastic syndromes. Leuk. Lymphoma. 45 (10):2099-104.
40.       Candoni A, Silvestri F, Bounamici S, Li D, Reddy P, Galili N, Nucifora G, Raza A (2004). Targeted therapies in myelodysplastic syndromes: ASH 2003 review. Semin. Hematol.41 (2 suppl. 4):13-20.
41.       Pritchard CC, Akagi L,Reddy PL,Joseph L, Tait JF (2010). COLD PCR enhanced melting curve analysis inproves diagnostic accuracy for kRAS mutations. BMC Clinical Pathology (In press